Abstract
The allelic relationships between a series of independently-induced adenine mutants of Coprinus lagopus were investigated, and limited complementation maps of three of the loci constructed. By means of nutritional tests and a search for aminoimidazole accumulants in the mycelium the adenine loci were correlated with steps in the purine biosynthetic pathway. Four loci can be assigned to (unknown) steps preceding closure of the imidazole ring, two others to specific steps occurring after closure of the ring. One of these latter represents a deficiency in the enzyme adenylosuccinase.
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