Abstract
Abstract The oncogenic purine derivative, guanine 3-oxide, was oxidized at position 8, and the N-oxide function was reduced by the rat, leading to 8-hydroxyguanine 3-oxide, 8-hydroxy-guanine, and guanine. A small amount was deaminated to 3-hydroxyxanthine. The guanine formed gave rise to some labeling of the purine bases of the RNA and DNA. There was no evidence of significant incorporation of guanine 3-oxide-8-14C into RNA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
