Abstract

The gastrointestinal neurohormones of reptiles have been poorly characterized structurally. Neurotensin has been purified to apparent homogeneity from an extract of the small intestine of the alligator, Alligator mississipiensis. The primary structure of the peptide (pGlu-Leu-His-Val-Asn-Lys-Ala-Arg-Arg-Pro-Tyr-Ile-Leu) is identical to that of chicken neurotensin. The data provide further evidence for a close phylogenetic relationship between crocodilians and birds.

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