Abstract

Pure ovarian choriocarcinoma can be gestational or nongestational in origin. Nongestational choriocarcinoma of the ovary is extremely rare, and its diagnosis is very difficult during the reproductive years. We present a case of a 33-year-old woman diagnosed with pure nongestational ovarian choriocarcinoma. Following surgery, multiple courses of a chemotherapy regimen of etoposide, methotrexate, and actinomycin-D (EMA) were effective.

Highlights

  • Choriocarcinoma of the ovary is a rare aggressive tumor, which may be either gestational or nongestational in origin

  • Most occurrences are gestational in origin and usually metastasize to the ovary from a uterine or tubal choriocarcinoma

  • Pure nongestational choriocarcinoma of the ovary (NGCO) is extremely rare, and diagnosis is very difficult in women of reproductive age [1,2]

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Summary

Introduction

Background Choriocarcinoma of the ovary is a rare aggressive tumor, which may be either gestational or nongestational in origin. Most occurrences are gestational in origin and usually metastasize to the ovary from a uterine or tubal choriocarcinoma. Pure nongestational choriocarcinoma of the ovary (NGCO) is extremely rare, and diagnosis is very difficult in women of reproductive age [1,2]. We present a case of pure NGCO occurring in a 33-year-old woman with a brief review of the literature.

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