Abstract

Introduction. Hepatic peribiliary cysts (HPCs) usually originate due to the cystic dilatation of the intrahepatic extramural peribiliary glands. We describe our rare experience of pure laparoscopic left hemihepatectomy (PLLH) in a patient with HPCs accompanied by a component of biliary intraepithelial neoplasia (BilIN). Case Presentation. A 65-year-old man was referred for further investigation of mild hepatic dysfunction. Contrast-enhanced computed tomography showed dilatation of the left-sided intrahepatic bile duct, and biliary cytology showed class III cells. The patient was highly suspected of having left side-dominated cholangiocarcinoma and underwent PLLH. Microscopic findings revealed multiple cystic dilatations of the extramural peribiliary glands; hence, this lesion was diagnosed as HPCs. The resected intrahepatic bile duct showed that the normal ductal lumen comprised low columnar epithelia; however, front formation on the BilIN was observed in some parts of the intrahepatic bile duct, indicating that the BilIN coexisted with HPCs. Conclusion. We chose surgical therapy for this patient owing to the presence of some features of biliary malignancy. We employed noble PLLH as a minimally invasive procedure for this patient.

Highlights

  • Hepatic peribiliary cysts (HPCs) usually originate due to the cystic dilatation of the intrahepatic extramural peribiliary glands

  • biliary intraepithelial neoplasia (BilIN) has to be accompanied by HPCs to progress to cholangiocarcinoma; there are no known reports of this process

  • We describe our rare experience with pure laparoscopic left hemihepatectomy (PLLH) in a patient with HPCs accompanied by a component of BilIN

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Summary

Introduction

Hepatic peribiliary cysts (HPCs) are a poorly recognized liver disease characterized by multiple tiny cysts along the portal radicle. HPCs usually originate due to the cystic dilatation of the intrahepatic extramural peribiliary glands around the intrahepatic large bile ducts [1]. HPCs sometimes cause stricture of the intrahepatic bile duct, they are thought to have malignant potential for cholangiocarcinoma [2, 3]. BilIN has to be accompanied by HPCs to progress to cholangiocarcinoma; there are no known reports of this process. Pure laparoscopic major liver resection is associated with concerns about intraoperative and postoperative morbidities [4, 5]. We describe our rare experience with pure laparoscopic left hemihepatectomy (PLLH) in a patient with HPCs accompanied by a component of BilIN

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