Abstract

Multiple light sources can be used for photodynamic therapy (PDT) with good results, but there are few comparative studies. This study compares the efficacy of treatment of basal cell carcinoma with PDT and two light sources, the non-coherent red light and pulsed dye laser 595 nm. In this small pilot study red light is more effective, but many more studies are needed to draw definitive conclusions.

Highlights

  • A small pilot study was performed selecting superficial histologically confirmed basal cell carcinoma (BCC) with a diameter greater than 3 centimeters

  • Red light LED is probably the most used for conventional photodynamic therapy (PDT) [1] and pulsed dye laser 595 nm (PDL) is among the coherent light the most appropriate for PDT its parameters have not been well defined [2]

  • Our objective was to compare both light sources in methylaminolevulinic acid (MAL) PDT for superficial basal cell carcinoma (BCC)

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Summary

Introduction

A small pilot study was performed selecting superficial histologically confirmed BCC with a diameter greater than 3 centimeters. A variety of light sources, coherent and not coherent, have been demonstrated efficacy in photodynamic therapy (PDT) but there is an absence of comparative studies in clinical practice. Red light LED is probably the most used for conventional PDT [1] and pulsed dye laser 595 nm (PDL) is among the coherent light the most appropriate for PDT its parameters have not been well defined [2].

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