Abstract
Objective: Arterial stiffness (AS) is a marker of arterial aging or arterial damage caused for pathologic processes, such as hypertension (HTN), leading to an increased risk for cardiovascular (CV) events, such as stroke and myocardial infarction. Many papers and clinical trials have been either published or designed evaluating this relationship and the methodology is now available to be used in clinical practice thanks to new portable devices, aiming to discover which patients are at higher risk or should have their treatment revised in order to promote greater CV protection. Design and method: We performed the evaluation of 375 patients at a private HTN clinic in order to assess the pressure wave velocity(PWV), augmentation index @75bpm and the central systolic and diastolic arterial pressure during the regular visits after explaining the process to the patients, according to ESC blood pressure reading guidelines, using a Mobil O’Graph device by IEM. The data were collected and then evaluated. Results: 375 patients were evaluated in order to obtain the PWV, central arterial pressure and augmentation index @75bpm. 46,9% of the sample were male, with average age of 49.5 years old. Only 12.5% of the patients had a prior cardiovascular event (AMI or stroke). The mean BMI was 27.5% The mean pulse wave velocity was 7.6+−2.4m/s and was higher in the subgroup of patients who had suffered a previous cardiovascular event (10.3+−2,4m/s), confirming the relationship between arterial stiffness and increased cardiovascular risk. The augmentation index did not show any relationship to cardiovascular risk. The mean central systolic pressure was 131.4 +−19.9mmHg and 81.3+−12.7 for diastolic central pressure. Conclusions: Arterial stiffness represents a CV risk factor which can be assessed through the evaluation of PWV and central pressure. The incorporation of this new technology using portable devices is feasible and very useful to identify high risk patients and be performed at a clinical setting.
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