Abstract
• Three patients with pyoderma gangrenosum were treated with suprapharmacologic doses of methylprednisolone sodium succinate using a five-day pulse therapy regimen. This therapy produced a dramatic remission with minimal side effects. The effects of pulse therapy are reviewed, and its role in severe steroid-responsive dermatoses is discussed. (<i>Arch Dermatol</i>1982;118:76-84)
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