Abstract
The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market.
 The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba.
 Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba.
 Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research.
 Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced.
 Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued
Highlights
There is a trend towards the use of natural ingredients of plant origin in the pharmaceutical industry
One of these plants, which contain a number of biologically active compounds and can be used as medicinal raw materials, are members of the family Ranunculaceae
The results of this study indicate the absence of any toxic manifestations when administered intragastrically at doses of 5000, 10,000 and 15,000 mg / kg in white rats, which allows to include extracts of callus mass Pulsatilla alba to class VI toxicity
Summary
There is a trend towards the use of natural ingredients of plant origin in the pharmaceutical industry. That is why the search for new sources of biologically active compounds is a topical issue in modern pharmacy [1]. One of these plants, which contain a number of biologically active compounds and can be used as medicinal raw materials, are members of the family Ranunculaceae. Many of these plants are threatened with extinction and are listed in the Red List [2]. The aim of the research is to present data from a review of the scientific literature on the area of distribution, content of biologically active substances and the spectrum of use in pharmacy Pulsatilla alba
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