Abstract
The clinical entity of polycystic ovarian syndrome (PCOS) coexisting with underlying hypothalamic amenorrhea (HA) has been formally described recently. We have previously reported in a pilot study (Dubourdieu et al, 2012), that pulsatile GnRH therapy was an effective and safe method of ovulation induction in this specific subgroup of infertile women, in comparison with gonadotropins treatment. The aim of this study was to confirm our preliminary results in a larger cohort of HA/PCOS women.
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