Abstract

Background: This article will review different materials for the treatment of pulps of primary and young permanent teeth. However, innovations in materials and advances in biology suggest that there may soon be a convergence of therapies for teeth of either dentition needing pulp treatment. Objectives: The objective of this study was evaluated the pulp and liver response to biocompatible agents such as lyophilized bone in comparison with classical formocresol. Materials and Methods: Treatment was applied to the upper right and left first molar of each animal, for a total of 120 teeth. Six groups were established according to the agent used and the time elapsed (30, 45 and 60 days). In each group five livers were selected, and a control group subjected to no treatment was also evaluated. At the end of the study the rats were sacrificed and the samples were processed for histological evaluation. Analysis of variance (ANOVA) for repeated measures was used. Results: Dentinal bridge formation and reparative dentin reached higher values in the group treated with lyophilized bone. The formocresol treatment group showed increased inflammation and necrosis. Conclusions: Lyophilized bone afforded improved pulp tissue response. No histological evidence of liver damage was observed in any of the hepatic samples studied.

Highlights

  • This article will review different materials for the treatment of pulps of primary and young permanent teeth and describe new therapies that might supplant them in the future.A pulpotomy in a young permanent tooth is undertaken to promote apexogenesis; under these conditions, retention of the vitality of the radicular pulp is imperative

  • Innovations in materials and advances in biology suggest that these may soon be a convergence of therapies for teeth of either dentition needing pulp treatment [1]

  • Pulp exposure was carried out with FMC treatment followed by zinc oxide-eugenol (ZOE) paste, or with lyophilized bone likewise followed by ZOE paste

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Summary

Introduction

This article will review different materials for the treatment of pulps of primary and young permanent teeth and describe new therapies that might supplant them in the future.A pulpotomy in a young permanent tooth is undertaken to promote apexogenesis; under these conditions, retention of the vitality of the radicular pulp is imperative. This article will review different materials for the treatment of pulps of primary and young permanent teeth and describe new therapies that might supplant them in the future. Based on pulpal biocompatibility and good sealing ability, a growing interest in more biocompatible materials promotes lyophilized bone as an alternative to tradicional medicaments. Lyophized bone can preserve pulpal health and promote healing with pulp regeneration in primary and permanent teeth. This material has been employed as an off-the-shelf grafting in periodontal osseous defects[2]. This article will review different materials for the treatment of pulps of primary and young permanent teeth. Objectives: The objective of this study was evaluated the pulp and liver response to biocompatible agents such as lyophilized bone in comparison with classical formocresol. No histological evidence of liver damage was observed in any of the hepatic samples studied

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