Pulmoner Alveolar Mikrolitiazis

Abstract

Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by extensive intraalveolar calcium and phosphate deposition. Here, we present a case of PAM in a 26-year-old female. The patient had persistent dry cough. Clinical presentation, radiological findings and transbronchial biopsy results were consistent with PAM. Scintigraphy revealed the absence of Tc-99m methylenediphosphonate uptake of lungs. Familial occurrence was observed. Radiological findings, pulmonary functions, and clinical status of the patient have remained stable for 24 months. Tc-99m uptake may not be observed at the early stages of this disease. Our case is at the early stage of the disease with regard to clinic, radiographic and scintigraphic findings. Family screening of PAM index cases to detect the disease in early asymptomatic stage is important.