Abstract

Editorial Notes1 October 1970Pulmonary Toxicity of IsocyanatesJOHN M. PETERS, M.D., RAYMOND L. H. MURPHY, M.D.JOHN M. PETERS, M.D.Search for more papers by this author, RAYMOND L. H. MURPHY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-4-654 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn our plastic world polyurethanes have achieved great commercial importance. The production of polyurethane involves the combination of chemicals containing two highly reactive isocyanate groups with a polyol. It is during this mixing and foaming process that the isocyanates are evolved into the workroom atmosphere. Depending on plant configuration and ventilation, few or many workers can be exposed. Other significant exposures may occur in industrial chemical laboratories and during repair or cleaning of the equipment. The products are used primarily as cushioning materials (mattresses, pillows, seat cushions, and packing materials), for insulation (thin-walled refrigerators and ovens), for soft toys, and...

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