Abstract
An intrapancreatic injection of bile and trypsin was employed to induce acute pancreatitis in dogs. This method was shown to produce, consistently, a picture of acute hemorrhagic pancreatitis documented by examination of the pancreatic pathology and by measurement of the serum amylase. Surface activity of lung washings from the pancreatitic dogs was also measured. There was a decrease in the surface activity of the affected dogs' lung washings. Light microscopy demonstrated alveolar atelectasis and vascular congestion in these animals' lungs.
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