Abstract
After exposing the lung to an immunizing dose of antigen, a coordinated series of cellular and mediator responses result in the induction of pulmonary immunity that defends the lung. Although these cellular and molecular events are not fully understood, studies have helped clarify the mechanisms responsible for the induction of immunity to primary antigen exposures and the development of localized immune responses after antigen challenges. This presentation will discuss the cellular responses important in the induction of immunity after a primary exposure to antigen, the recruitment of lymphocytes into the lung, the response of pulmonary immune memory cells to antigen challenges, and the induction of long-term antibody production in the lung.
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