Abstract

Two cases of pulmonary nocardiosis occurred in the primate colony of the Yale University School of Medicine from 1961–1965. During this same period 22 monkeys were necropsied with tuberculosis. Pulmonary nocardiosis may be mistaken grossly and microscopically for tuberculosis. Although the gross appearance of the lungs in both diseases may be indistinguishable, there are important differential points. Pulmonary nocardiosis has the following features which tend to differentiate it from pulmonary tuberculosis: No tracheobronchial lymph node involvement, No extra-thoracic lesions, and Demonstration of typical organisms on direct smear.

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