Abstract
BackgroundNocardiosis is an uncommon opportunistic infection seen in immunocompromised patients or those with a dysfunctional immune system. Nocardia asteroides infection in patients with Pemphigus foliaceus (PF) has never been reported.Case presentationWe report an interesting case of nocardiosis-characterized by pulmonary intra-cavitary infection, in a 54-year-old man with PF and diabetes mellitus. The man finally recovered from the infection.ConclusionsThis is the first case reporting pulmonary nocardiosis in a patient with PF. We recommend that physicians be aware of nocardiosis in patients with pemphigus as a possible cause of underlying infectious disease to avoid misdiagnoses and mismanagement.
Highlights
Nocardiosis is an uncommon opportunistic infection seen in immunocompromised patients or those with a dysfunctional immune system
We present a rare case, in which immuno-supression was further potentiated by diabetes mellitus, resulting in an opportunistic pulmonary infection with Nocardia asteroides
Pemphigus is a rare but serious chronic blistering disorder of the skin and mucous membranes [2]. It is usually categorized into two distinct forms, Pemphigus vulgaris (PV) and Pemphigus foliaceus (PF), each with its own variants(e.g. The endemic form of PF, known as Fogo selvagem (FS)) [3,4,5]
Summary
Nocardiosis is an uncommon opportunistic infection seen in immunocompromised patients or those with a dysfunctional immune system. We present a rare case, in which immuno-supression was further potentiated by diabetes mellitus, resulting in an opportunistic pulmonary infection with Nocardia asteroides. A 54-year-old man with diabetes mellitus was admitted to Maoming People’s Hospital on 26, April 2020.
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