Abstract

During the period of investigation (Oct. 2015 to Sept. 2022), a total number of 50 cattle in different areas of Sohag Governorate, South Egypt, were necropsied due to the bad-sequel of BRD. They were unvaccinated against respiratory infection and did not respond to the therapeutic trails by fieldveterinarians. Their lungs grossly described and culturally examined for the presence of Mycoplasma infection. Grossly, the affected lungs showed multiple areas of pulmonary sequestration in 41/50 (82.00%) of the tested cases with remarkable thickening and fibrosis of the interlobular septa. Caseonecrotic bronchopneumonia with bronchiectasis and the small airways filled by yellowish caseated purulent exudate was discerned. All culturally examined lungs (50 cases) were Mycoplasma positive. The majority (90 %) of the isolated Mycoplasma strains were biochemically glucose and arginine negative with production of film and spots. The PCR—tested strains were Mycoplasma bovis infection. The obtained results are strongly denotes Mycoplasma bovis is a major persistent pneumonic pathogen of BRD in Sohag Governorate and it is concluded that vaccination program against the most common pneumogens including Mycoplasma bovis should be regularly warranted.

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