Abstract
Mucormycosis is a devastating fungal infection which usually occurs in patients with diabetic ketoacidosis, chronic renal failure, haematological malignancies, or solid organ transplant recipients. Pulmonary mucormycosis may present as an unresolving pneumonia, multiple nodules, or a cavitating abscess, and is associated with an overall 80% mortality. The probable diagnosis of mucormycosis requires the combination of various clinical data and the isolation of the fungus from clinical samples. Treatment requires a rapid diagnosis, correction of predisposing factors, surgical resection, debridement and appropriate antifungal therapy. We are reporting a successfully treated case of culture proven pulmonary mucormycosis in non-diabetic ESRD patient.
Highlights
Patients with end-stage renal disease (ESRD) are more susceptible to systemic infections with worse outcome [1,2]
Mucormycosis term is used for infections caused by fungi which belong to the order mucorales, first described by Paltauf [3,4]
The spores released by them can become airborne and inhalation can lead to germination and hyphae formation, leading to variety of infections for example rhinocerebral, pulmonary, cutaneous, gastrointestinal and disseminated forms [5,6]. This case report illustrates that early detection and instant aggressive therapy leads to a successful outcome in non-diabetic ESRD male diagnosed by rapid microbiology analysis of broncho alveolar lavage (BAL)
Summary
Patients with end-stage renal disease (ESRD) are more susceptible to systemic infections with worse outcome [1,2]. The spores released by them can become airborne and inhalation can lead to germination and hyphae formation, leading to variety of infections for example rhinocerebral, pulmonary, cutaneous, gastrointestinal and disseminated forms [5,6]. This case report illustrates that early detection and instant aggressive therapy leads to a successful outcome in non-diabetic ESRD male diagnosed by rapid microbiology analysis of broncho alveolar lavage (BAL). Microscopy of sputum revealed occasional gram positive cocci, conidia and hyphae like structures on gram staining, lacto phenol cotton blue film confirmed the presence of fungal elements, acid fast bacilli were negative.
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