Abstract
Hepatocellular carcinoma is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, particularly viral hepatitis. The diagnosis of hepatocellular carcinoma can be difficult, and often requires the use of serum markers, one or more imaging modalities, and histological confirmation. The authors describe a case of a 26-year-old woman with hepatocellular carcinoma and multiple pulmonary metastases. She presented with hepatomegaly and sporadic fever, and had negative hepatitis serology, normal alkaline phosphatase, and a rising serum alpha-fetoprotein level. The diagnosis was confirmed by histopathology, after percutaneous liver biopsy. Although the patient was in good health condition and had few symptoms, there was no possibility of treatment due to the extension of the liver tumor and the number of pulmonary metastases.
Highlights
Hepatocellular carcinoma (HCC) is the main primary hepatic tumor and one of the most common cancers worldwide [1]
Hepatocellular carcinoma is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, viral hepatitis
The main risk factors associated with HCC are hepatitis C virus (HCV) or hepatitis B virus (HBV) infection and alcoholic cirrhosis; chronic hepatitis B is the most frequent cause [3]
Summary
Hepatocellular carcinoma (HCC) is the main primary hepatic tumor and one of the most common cancers worldwide [1]. Abstract Hepatocellular carcinoma is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, viral hepatitis. The diagnosis of hepatocellular carcinoma can be difficult, and often requires the use of serum markers, one or more imaging modalities, and histological confirmation. The authors describe a case of a 26-year-old woman with hepatocellular carcinoma and multiple pulmonary metastases.
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