Abstract
Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma. Pulmonary MALT lymphoma is considered to originate from bronchial MALT and is also referred to as bronchial-associated lymphoid tissue lymphoma. Pulmonary MALT lymphoma is a rare disease, but it is the most frequent subset of primary pulmonary lymphoma. The median age at diagnosis of pulmonary MALT lymphoma is 50–60 years, with only few patients aged <30 years. This is the case report of a 19-year-old patient with pulmonary MALT lymphoma presenting with a multiple pulmonary consolidation pattern on computed tomography scans, who underwent successful chemotherapeutic treatment with a chlorambucil-based regimen.
Highlights
Mucosa‐associated lymphoid tissue (MALT) lymphomas were first described in 1983 by Isaacson and Wright, have since been recognized as a separate entity and account for 8‐10% of all non‐Hodgkin lymphomas [1]
The optimal therapy for this rare disease remains under debate and some cases of pMALToma are managed with the watch‐and‐wait approach
Diagnosis for pMALToma is 50‐60 years [5], with only few patients aged
Summary
Mucosa‐associated lymphoid tissue (MALT) lymphomas were first described in 1983 by Isaacson and Wright, have since been recognized as a separate entity and account for 8‐10% of all non‐Hodgkin lymphomas [1]. Pulmonary MALT lymphoma (pMALToma), referred to as bronchial‐associated lymphoid tissue lymphoma [2], is a rare disease. The optimal therapy for this rare disease remains under debate and some cases of pMALToma are managed with the watch‐and‐wait approach. This is the case report of a 19‐year‐old patient with pMALToma presenting with multiple pulmonary consoli-. Spiral lung CT revealed bilateral multiple pulmonary consolidations, with the largest lesion sized ~4.5x4.5 cm (Fig. 1). The microscopic examination revealed lymphoepithelial lesions characterized by diffuse infiltration of the lung parenchyma by small lymphocytes, monocytoid cells and plasma cells (Fig. 2). After 2 cycles of chemotherapy, all the pulmonary lesions were significantly reduced in size (Fig. 3).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
