Abstract
Pulmonary lesions in seven patients with malignancy who were treated with bleomycin were studied at autopsy. Six of them had symptoms of respiratory distress. The lesions showed a predilection for the lower lobe and subpleural zones. Diffuse alveolar damage progressing to interstitial pneumonitis at varying stages of evolution was observed in all cases. The changes included intra-alveolar proteinaceous exudate, extensive interstitial fibrosis and frank epithelial dysplasia simulating metastatic nodules.
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