Abstract

Venous thromboembolism is one of the complications in patients prescribed antipsychotic medications. Neuroleptic malignant syndrome (NMS) is a rare side effect of antipsychotic medications in this population. In this case, a young patient, who presented with NMS after a recent start of antipsychotic medications, had developed a pulmonary embolism despite standard of care measures of venous thromboprophylaxis and early mobilization. A low threshold of VTE suspicion and effective preventive measures are both required in order to avoid this preventable complication in this population.

Highlights

  • S 226×109/L (150-450 ×109/L), and creatinine kinase 3792 U/L (30-300 U/L)

  • A young patient, who presented with Neuroleptic malignant syndrome (NMS) after a recent start ly of antipsychotic medications, had developed a pulmonary embolism despite stann dard of care measures of venous thromboo prophylaxis and early mobilization

  • It was first described in o 1960.1 NMS has been recognized and c described since that time especially with the - increasing use of antipsychotic medican tions

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Summary

Introduction

S 226×109/L (150-450 ×109/L), and creatinine kinase 3792 U/L (30-300 U/L). Serum electrolytes level, blood urea nitrogen, and creatinine were normal. Cial Introduction er Neuroleptic malignant syndrome (NMS) is a rare but serious psychiatric m emergency condition classically found in patients who have started taking antipsym chotic medications. It was first described in o 1960.1 NMS has been recognized and c described since that time especially with the - increasing use of antipsychotic medican tions. On day 3, he was oriented, communicating normally, and fully mobile with a gradual improvement in his creatinine kinase. He complained of one episode of a small amount of hemoptysis. Antipsychotic medications in the last two started atypical antipsychotic medications is years had a 32% higher risk of VTE comdescribed

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