Abstract
Arterial stiffness had been proposed as the cause of sub-clinical left ventricular dysfunction in patients with COPD. Vascular studies in COPD patients were mainly assessed by carotid-femoral (aortic) pulse wave velocity using micromanometer applanation tonometry. The evaluation of pulmonary artery (PA) elasticity in COPD has not been assessed. This study seeks to evaluate indices of PA stiffness in patients with COPD. We hypothesized that patients with COPD would have increased pulmonary artery stiffness compared to healthy individuals. To test this we determine the pulmonary artery area change (distensibility or pulsatility in %) by cardiac magnetic resonance imaging (MRI) and related PA distensibility to the severity of COPD.
Highlights
Arterial stiffness had been proposed as the cause of subclinical left ventricular dysfunction in patients with COPD
We hypothesized that patients with COPD would have increased pulmonary artery stiffness compared to healthy individuals
Participants with COPD had increased pulmonary artery (PA) stiffness compared to normals as shown in Table 1, statistical significance was not attained in the sample recruited to date (P-trend across the categories of COPD severity, 0.2)
Summary
Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) - the mesa copd study. Chia-Ying Liu1*, Rui Jiang, Stephen Dashnaw, Aditya Jain, Antoinette Gomes, James Carr, David A Bluemke, Joao Lima, Martin Prince, Graham Barr. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
