Abstract
Pulmonary arterial and systemic pressure measurements were obtained in 51 normal full-term infants ranging from 1 to 54 hours of age by retrograde catheterization of the aorta, ductus arteriosus, pulmonary artery, and right ventricle via the umbilical artery. A left-to-right shunt through the ductus arteriosus was demonstrated in the majority of the infants under 15 hours. Pulmonary arterial pressure does not fall abruptly after the establishment of respiration. The systolic pressure level approximates that in the aorta during the first few hours of life and is accompanied by a drop in diastolic pressure. Mean pulmonary arterial pressure approaches the 50 per cent value of mean systemic pressure by the end of the first day.
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