Abstract

Objective To describe the clinical feature of pulmonary alveolar microlithiasis (PAM)and heighten the ratio of diagnosis. Methods Three cases of PAM from this hospital were presented. The literatures related to PAM were searched through Chinese Biomedical Disk, and the data of all the cases were retrospectively analyzed. Results A total of 120 cases were collected, including 70 male and 50 female patients. The main clinical manifestations included cough (n = 51 ), dyspnea (n = 49 ),expectoration ( n = 26), chest pain ( n = 18), chest distress ( n = 17), palpitation ( n = 4), hemoptysis ( n =3). Pulmonary function test showed normal findings in 7 cases, restrictive ventilatory disorder and decreased diffusing capacity for carbon monoxide in 12 cases. Chest X-ray was performed in 120 cases.Profusion of micro nodules were present in 106 cases, normal hilum in 104 cases, pericar dialseptum vague in 55 cases, linear subpleural calcification in 48 cases, and apex pulmonis emphysema in one case.Conclusions As an uncommon disease, PAM is often underdiagnosed and misdiagnosed. High resolution computerized tomography and fibro-bronchoscopy are helpful for confirmation of the diagnosis. Key words: Pulmonary alveolar microlithiasis; Tomography,X-ray computed

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