Abstract
AbstractReactions between readily available 2‐alkynylanilines and activated ketones such as β‐keto esters promoted by p‐toluenesulfonic acid afford 4‐alkyl‐2,3‐disubstituted quinolines in good to excellent yields. The generality of substituents at the other end of the triple bond of 2‐alkynylanilines makes the method a valuable approach to diversified 4‐alkylquinolines, which are difficult to obtain by classical methods such as the Friedländer reaction. Quinoline dimers can be prepared efficiently with alkyl or aryl linkers at C‐4.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
