Abstract
The common intact-PTH assay detects not only PTH (1-84) but also PTH (7-84) fragment. Recently, it is reported that PTH (7-84) fragment is the antagonist to PTH (1-84) biological action. Thus, conventional intact-PTH assay might mislead the overestimation of parathyroid function in uremic patients. Whole PTH assay, which detect only PTH (1-84) fragments may be useful for more precise evaluation of PTH activity in uremic patient.
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