Abstract

<h3>Introduction</h3> Catheter related sepsis (CRS) can result in disrupted feeding, parenteral nutrition (PN) waste, systemic sepsis, central vein thrombosis and potential prolonged hospital stay in inpatients receiving PN. Alcohol-impregnated disinfection caps reduce CRS in home PN patients<sup>1</sup>and hospital inpatients with indwelling central lines.<sup>2</sup>Their role in reduction of CRS in inpatients receiving PN is less clear. <h3>Method</h3> Prospective data from inpatients receiving PN from April 2013 to January 2015 was assessed. CUROS<sup>TM</sup>line caps were introduced on 8/09/14 in addition to an existing standard aseptic non-touch technique for all patients receiving PN. Patients received PN via a peripherally inserted central catheter or a dedicated port of a central venous catheter. CRS were analysed in patients without and with the CUROS<sup>TM</sup>device and expressed as events/1000 catheter days. CRS was confirmed by a positive culture from blood withdrawn from the line or from line tip culture. <h3>Results</h3> There were no differences in baseline characteristics between the 2 groups (Table 1). In the 17 months prior to the caps being used the incidence of line infections in patients receiving PN was 6.17/1000 line days. In the 5 months after their introduction this fell to 0.00/1000 line days (p-value 0.014) <h3>Conclusion</h3> Upon introduction of a simple alcohol-impregnated disinfection cap there has been a significant fall in CRS rates related to PN. The cost to the Trust of a CUROS<sup>TM</sup>cap is £0.32 and further assessment of the cost saving to the Trust will be undertaken. <h3>Disclosure of interest</h3> None Declared. <h3>References</h3> Small M. The impact of 70% isopropyl alcohol port protection caps on catheter related bloodstream infection in patients on home parenteral nutrition. <i>Poster, World Congress Vascular Access </i>2014 Merrill KC, Sumner S, Linford L, <i>et al</i>. Impact of universal disinfectant cap implementation on central line-associated bloodstream infections. American Journal of Infection Control 2014;42:1274–7

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