Abstract
In the Indian Ayurvedic system of medicine the heart wood of Bijasar (Lat: Pterocarpus marsupium; Fam: Leguminaceae) has been extensively used to treat diabetes mellitus. Detailed chemical and HPTLC analysis has been performed to identify a reliable marker for quality control of Pterocarpus marsupium and to check commercial samples for authenticity and purity. The two anti-diabetic principles viz. pterostilbene (1) and marsupsin (2) were isolated by extensive chromatographic screening of its ethyl acetate extract. HPTLC studies of these two compounds revealed that levels of pterostilbene are several times more than that of marsupsin both in plant samples and in commercial formulations. The HPTLC method gave reproducible results and response was linearly dependent on amount analysed in the range 200–500 ng. Pterostilbene can therefore be regarded as a reliable marker for evaluation of the quality of Pterocarpus marsupium.
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