PT014 A novel microwave catheter with a toroidal radiation pattern can form circular lesions on endocardial ablation

Abstract

O ST E R A B ST R A C T S have shown that insertion of implantable cardioverter defibrillators(ICD) reduce mortality in these patients. However, the insertion of these devices in the UK is still directed by national guidelines and cost. Real-life data showing the mortality benefit of ICD insertions in patients with DCM in UK is lacking. Objectives: We evaluated long-term mortality and survival in patients with DCM from a large sample from Manchester,UK. Methods: Anonymous information on patients with DCM, co-morbidities and procedures attending seven-hospitals in Manchester, UK in the period 2000-2013 was obtained from the local-health-authority-computerised hospital-activity-analysisregister using ICD-10 and OPCS coding-systems. Logistic-regression-analysis was used for predictors of mortality and survival was determined by Kaplan-Meiercurves. Results: Over the time period, there were 725patients with DCM; mean age 53.9years 15.5(S.D); Male(530,73.1%), Female(195,26.0%). Of these 198 patients died(27.3%). The main co-morbidities were HeartFailure(400;55.2%), AtrialFibrillation(249;34.3%), Hypertension(248;34.2%), IschaemicHeartDisease(144;19.9%), Type2DiabetesMellitus(126;17.4%), ChronicKidneyDisease(70;9.7%). 43patients(5.9%) had ventricular tachyarrhythmias and 47patients(6.5%) had ICD inserted. A logistic-regression-model showed only increasing age(RR1.02; C.I1.01-1.03), IschaemicHeartDisease (RR1.97;C.I 1.21-3.21) and ChronicKidneyDisease (RR4.73;C.I2.51-8.91) to be significant predictors of worsened mortality in this population. Insertion of ICD(RR0.16;C.I0.06-0.48) and Hypertension (RR0.61;C.I0.39-0.96) were found to be significant predictors of improved mortality (Figure1).