Abstract
The authors compared bilateral recordings of electrodermal activity and conjugate lateral eye movements in two groups (10 men and 10 women each) of college students: high-risk nonpatients with subsyndromal depression and normal control subjects. Like acutely depressed patients, the high-risk subjects showed smaller right- than left-hand skin conductance response amplitudes to neutral tones. This group also showed a bias toward left-tending conjugate lateral eye movements in response to various cognitive problems. Control subjects showed symmetrical responses on all electrodermal activity measures and question-specific conjugate lateral eye movements. These data are tentatively interpreted as reflecting right-hemisphere hyperexcitability in affective illness.
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