Abstract
Effects on psychological and physiological variables of four doses of intravenously infused 1-adrenaline (0.05, 0.10, 0.15, and 0.20μg/kg body wt/min) and a placebo solution, were examined in five subjects. In general the dose-response curves showed progressive increase in response with increasing dose-levels of the drug. The changes in heart rate, blood pressure and subjective stress were pronounced, while the concomitant improvement in a performance test was slight. There were marked differences between the time-response patterns of the different variables in that the physiological changes remained relatively constant throughout each infusion period, whereas the subjective reactions decreased towards the end of the infusion.
Published Version
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