Abstract

Background : Our aim was to study the relationship between hormonal disturbances and psychopathology in Eating Disorders (ED). Methods : Forty-nine women diagnosed as Eating Disorders according to DSM-IV were subjected to control plasma levels of TSH, FT3, FT4, LH, FSH, 17beta-estradiol, prolactin, cortisol, DHEAS, GH and IGF-1. They were also administered by SCL-90R, BAT, DES II questionnaires. We applied multivariate regression models. Results : Our results highlight a statistically significant relation between LH, FSH and prolactin decreased levels, mood and thought disturbances (subscales 3, 5, 7, 8 and 9 of SCL-90r) which are associated to Body Attitude ( BAT total scale) and Dissociative Experiences (DES II total scale). Conclusions : Decreased sexual hormones levels could have a role in ED psychological disturbances, not inquired yet

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