Psychological states regarding adjuvant chemotherapy in patients with non-small cell lung cancer

Abstract

BackgroundUnderstanding the anxieties and emotions of patients with lung cancer before and after radical surgery is crucial in the decision to undergo postoperative adjuvant chemotherapy. However, the psychological states and changes associated with adjuvant chemotherapy during perioperative periods in patients with non-small cell lung cancer (NSCLC) remain unclear. Patients and MethodsParticipants with a self-reported diagnosis of pathological stage II or III NSCLC who underwent complete surgical resection and received information on postoperative adjuvant chemotherapy (n = 101) were sampled from an online panel in Japan from October 9 to November 19, 2020. Eligible and consenting participants completed a self-administered online questionnaire survey about their disease, and their psychological states were assessed. ResultsThe majority of patients (39, 38.6%) were 60–69 years of age, and 87 (86.1%) were men. A total of 59 (58.4%) and 42 (41.6%) patients had pathological stages II and III, respectively. Regardless of the situation, more than 75% of the patients were anxious about the possibility of recurrence after complete surgical resection for lung cancer. Approximately 70% of respondents selected the option of “I will get adjuvant chemotherapy” on any precondition. Among them, almost all respondents selected the option “want to do everything I can do now to prevent recurrence.” ConclusionIn this small sample of respondents with NSCLC from Japan, it is important for surgeons and physicians to explain the condition and corresponding therapy for lung cancer, while considering the possibility of recurrence in any situation, even before surgery as a curative intent.