Psychological risk factors and selective prevention of panic disorder: Theoretical aspects and clinical implications

Abstract

Despite the high prevalence, and high functional impairment associated with panic disorder, programs targeting the prevention of panic psychopathology are still very limited. This article aims to guide panic disorder prevention programs, by analyzing different psychological risk factors, and their interactions in the pathogenesis of the psychopathology of panic disorder. The results show, on the one hand, that neuroticism, perceived control, emotional clarity, and anxiety sensitivity are causal risk factors for the development of panic disorder. On the other hand, several causal pathways involving complex chains of these factors lead to the development of panic disorder. These results may help guide panic disorder prevention interventions by guiding, on the one hand, decisions concerning the populations to be targeted for prevention efforts as well as, on the other hand, by identifying the risk and protective factors to be targeted to reduce the probability of occurrence of panic disorder.