Abstract

The aim of this work is approbation of the pathogenetically substantiated psycho­immunological rehabilitation of advanced cancer patients with psychogenic medical history. 17 advanced cancer patients (with 6 various types of cancer) took part in this study. All psycho­emotional disorders were diagnosed clinically and psychometrically (SCL 90). The treatment of signs and symptoms of mentioned disorders included hypnotherapy and psychotropic drugs. The specific anti­tumor activity of the immune system was assessed by the delayed type hypersensitivity skin reaction on the tumor­associated antigens. An activation of specific anti­tumor immunity was provided only after stable clinical effect of psycho-correction by specially developed methods of epicutaneous and modified extra­corporeal activation. The effective treatment of psycho­emotional disorders had a direct correlation with spontaneous increase in specific anti­tumor activity of the immune system (p < 0.0008). The catamnesis showed that only 5 advanced cancer patients, who were provided with whole course of psycho­immunological rehabilitation survived for 1.5 years and up to 7 years after psycho­immunological rehabilitation. The rest 12 patients died. This study showed some clinical opportunities of positive influence of special psycho­immunological rehabilitation on to the course of a disease of advanced cancer patients with psychogenic medical history. Key words: Advanced cancer, anti-tumor immunity, cancer rehabilitation, psycho-emotional disorders, psychogenic medical history.

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