Abstract

We report a case of an adult female who had changes suggestive of encephalomalacia in the magnetic resonance imaging (MRI) of the brain but presented with psychiatric symptomatology instead of neurological manifestations. Encephalomalacia is softening of brain tissue which may lead to brain changes and present with varied clinical manifestations. Most of the cases reported previously were on infants & children and almost all of them were related to neurological disorders. But cases with psychiatric symptomatology were rarely reported, that too in adults. The authors discussed the psychiatric symptom profile, their management and emphasized the importance of imaging of the brain and its association with psychiatric manifestations. Keywords: Encephalomalacia, Psychiatric morbidity, Brain imaging.

Highlights

  • Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.[1]

  • magnetic resonance imaging (MRI) of the brain with contrast revealed corticalsubcortical areas of encephalomalacia with gliosis in bilateral frontal lobes, left parietal lobe and bilateral cerebellar hemispheres which appeared to be sequelae of old insult

  • The MRI finding was unexpected in this particular case without any history of trauma and seizure

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Summary

Introduction

Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.[1]. Her interaction with her family members decreased and she used to get irritable on trivial issues. There was no history of any significant physical illness, trauma or head injury, visual disturbances and hearing voices.

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