Abstract
Claims have been put forward from time to time that there is a psychosomatic element in Parkinsonism, i,e. that certain types of personality or stress predispose towards the disease. The evidence is discussed. Certain biochemical abnormalities have been claimed in Parkinson cases—namely thar they have low levels of dopamine in the corpus striatum and excrete low levels in the urine. Levels of nor-adrenaline and serotonin are also apparently low. The evidence for the dopamine deficiency theory is discussed, and the role of acetylcholine and histamine considered.
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