PSY76 - US Lupus Trends 2009-2017: Results from the National Health and Wellness Survey

Abstract

Lupus is an autoimmune disease with no available cure, and a high physical and mental burden on the patient.1 The objective of this analysis was to examine lupus trends and outcomes across US adults from 2009-2017. This analysis utilized cross-sectional data from the US National Health and Wellness Survey (NHWS), part of PaCeR (Patient-Centered Research), from 2009 (n=75,000) through 2017 (n=75,004). Respondents were age ≥ 18 years, and results were weighted/projected to reflect the gender, age, and race/ethnic proportions, as determined by the Current Population Survey (US Census Bureau). Quality of life (QoL) was measured by the physical component score (PCS) and mental component score (MCS) of the Short Form (SF-12v2 / SF-36v2)2, 3. Loss of work/productivity was measured by the Work Productivity and Activity Impairment (WPAI) instrument.4 Prevalence of lupus was fairly similar from 2009 to 2017, ranging from 0.48% to 0.63%, which is comparable to estimates by the Lupus Foundation of America.5 Proportion of demographic characteristics and utilization fluctuated from year to year with the following ranges; white (50.0% to 60.7%), married (46.0% to 53.8%), male (15.1% to 21.6%), mean age (46.8 to 51.7), insurance coverage (87.1% to 94.8%), prescription usage (56.0% to 68.6%), healthcare provider visits (93.4% to 96.3%), emergency room visits (27.0% to 36.3%), hospitalization (16.6% to 27.2%). QoL outcomes as measured by the SF-36 showed physical component score ranged from 35.6 to 40.1, while mental component score ranged from 41.9 to 45.1. Less than half of the lupus population is employed with patients reporting between 11.6% and 23.6% absenteeism, 34.1% and 47.5% presenteeism and 39.1% and 52.8% work productivity loss. There have been fluctuating changes in demographic characteristics and utilization with patients experiencing significant impairment in QoL, work and productivity. Findings indicate there is still unmet need in patients with lupus.