PSXVI-8 Marine-Derived Ca-Mg Complex Influences Serum Metabolites, Colostrum Nutrient Profile, Lipid and Glucose Metabolism-Associated Genes Expression, and Stress Hormones in Sows Over a Four-Parity Period

Abstract

Abstract Among different nutrients, the requirement of minerals is small, but impacts sow longevity and reproduction performance. Cross bred gilts (n=72; average body weight 181 kg) in their 1st to 4th subsequent parity was randomly allocated to 1 of 3 treatments (24 gilts/treatment) to assess the effects of marine derived Ca-Mg complex supplementation on serum mineral contents, hormone concentrations, colostrum nutrient profile, as well as lipid and energy metabolism-associated genes expression in the placental, and umbilical cord tissues. Treatments consisted of CON (corn-soybean meal-wheat-based basal diet with limestone as main Ca source), CM1 (CON-MgO + 0.40% marine derived Ca-Mg complex formulated to have same Ca and Mg spec as basal diet), and CM2 (CON - 0.4% limestone + 0.4% marine derived Ca-Mg complex - MgO). The inclusion of Ca-Mg complex in sow diet increased (P< 0.05) the serum Ca and Mg levels, colostrum Ca, Mg, protein, and IgM contents, and reduced stress hormones after farrowing. However, depletion of Ca and Mg was observed in the 4th parity sows fed CON diet and a reduction in stress hormones were observed in 3rd and 4th parity sows. The relative expression of the SCD gene was downregulated in the umbilical cord of piglets born to CM1 and CM2 sows compared with the CON group during parity 3 (P= 0.007) and parity 4 (P = 0.009). During the parity 4, SLC2A2 (P = 0.003) and FABP4 (P = 0.043) genes expression were upregulated in the umbilical cord of piglets born to CM2 sows and placenta tissue of sows from CM1 group, respectively. The observed positive influence of marine-derived Ca-Mg complex on lipid and glucose metabolism-associated genes expression, serum metabolites, colostrum nutrient, and stress hormones suggests that inclusion of 0.4% Ca-Mg complex in the diet is beneficial for improving sow longevity and performance.