PSVII-3 Effects of oral administration of essential oils on anti-immune stress, antimicrobial and repairing the intestinal damage in broilers challenged by lipopolysaccharide

Abstract

Abstract The aim of the present study was to evaluate the effects of oral administration of essential oils (Carvacrol, Thyme and Oregano essential oils) on anti-immune stress, antimicrobial and repairing the intestinal damage, caused by Salmonella enterica Lipopolysaccharide, in vivo of broilers. A total of 100 ROSS 308 broilers (21-day-old; 1.10 ± 0.11kg) were randomly allocated to 5 groups, T1: basal diet + Saline; T2: basal diet + LPS; T3: basal diet+ 200μL carvacrol oils+ LPS; T4: basal diet+ 200μL thyme oils+ LPS; T5: basal diet+ 200μL oregano oils+ LPS, with 20 replicates every group, and 1 chicken per replicate per cage. The challenged by LPS resulted in an immune stress, which manifests as the abnormal growth (P < 0.05) in immune organs, the content of IgG (P < 0.05) and TNF-α(P < 0.05) and the rectum temperature (P < 0.05) increased compared with other groups; the oral administration of essential oils controlled the immune stress to a certain extent. The essential oils could withhold maleficent bacteria, as E. coli (P < 0.05) and Salmonella enumeration (P < 0.05), in vivo of the broiler. Meanwhile, the essential oils repaired the intestinal damage which shown a reduction in the villi height (P < 0.05) and goblet cell (P < 0.05) caused by LPS. In conclusion, the essential oils (Carvacrol, Thyme and Oregano essential oils) controlled the stress reaction and maintain intestinal health to a certain extent. http://www.conferenceharvester.com/