Abstract

IntroductionPsoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life. The Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) was the first disease-specific tool for determining the impact of the disease on the quality of life of people with PsA.ObjectivesThe primary objective was to develop and validate a Brazilian Portuguese version of the PsAQoL.MethodsThe UK PsAQoL was translated into Brazilian Portuguese using two translation panels. This translation then checked for face validity and construct validity with new samples of patients. Finally, a test-retest validation study was conducted with 52 patients with PsA. The survey included the Nottingham Health Profile (NHP) as a comparator instrument.ResultsInternal consistency and reproducibility were both excellent for the new adaptation (0.91 and 0.90 respectively Scores on the PsAQoL were found to correlate as expected with the comparator measure and the instrument was able to detect differences in score related to perceived severity of PsA, general health status and presence of a flare.ConclusionThe Brazilian PsAQoL was found easy to understand and complete and has excellent reliability and construct validity. The new measure will be a valuable new tool for use in routine PsA practice and clinical trials.

Highlights

  • Psoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life

  • The adaptation of the Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) consisted of three stages: translation; assessment of face and content validity; psychometric evaluation

  • An initial translation of the PsAQoL was produced by the bilingual panel

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Summary

Introduction

Psoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life. Psoriatic arthritis (PsA) is a chronic inflammatory disease that is part of the group of spondyloarthropathies, affecting up to 1% of the population [1] It is a complex diseasewhich, in addition to the cutaneous involvement, the patient presents musculoskeletal problems (related to the spine, enthesis and peripheral joints) and may present extra-muscular manifestations including the intestine or the eye [1]. The articular condition (arthritis, tenosynovitis, enthesitis and/or dactylitis) may significantly limit functional ability, including activities of daily living and employment. This may well lead to important socioeconomic impacts [4]

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