Abstract
We described a case of psoriasis possibly resulting from isotretinoin therapy in acne. A 17-year-old patient started treatment with oral isotretinoin (30mg of drug) due to acne vulgaris. After 4 weeks, of treatment, the patient complains for the presence of scattered erythematous plaques and papules. The clinical picture suggested psoriasis (this is also confirmed by histopathological study). The history revealed that the patients mother suffered from psoriasis for 30 years.J MEDICINE January 2017; 18 (1) : 37-38
Highlights
Isotretinoin acid (13-cis retinoic acid) is a synthetic analogue of vitamin A (I retinoids generation) and is one of the effective drugs in acne vulgaris.[1]
We described a case of psoriasis possibly resulting of acne, after 3 weeks of isotretinoin therapy
The patient showed no changes of psoriasis before treatment of isotretinoin and she has no changes which suggested that psoriasis were still before the treatment of isotretinoin
Summary
Isotretinoin acid (13-cis retinoic acid) is a synthetic analogue of vitamin A (I retinoids generation) and is one of the effective drugs in acne vulgaris.[1]. Isotretinoin is an extremely valuable drug that is occasionally associated with well-known side-effects, including cheilitis, retinoid dermatitis, palmoplantar desquamation, and photosensitivity.[2,3] We described a case of psoriasis possibly resulting of acne, after 3 weeks of isotretinoin therapy. Case Report A 17-year-old patient started treatment with oral isotretinoin due to acne vulgaris. The patient was taking 30mg of drug (daily, single dose); weighed 56 kg. After 2 months after discontinuation of the drug and the local treatment of psoriasis, the psoriatic lesions were decreased. Single lesions of psoriasis on the arms persisted for over a period of 6 months the following observations. 2. Department of Dermatology, 6th Military Support Unit, Ustka, Poland. 3. Department of Histology and Embryology with Experimental Cytology Unit, Medical University of Lublin, RadziwiBowska, Lublin, Poland.
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