Psoriasis: A Peer Review Article

Abstract

Psoriasis is a chronic inflammatory skin disease that is characterized by sharply demarcated Erythematous plaques with whitish scale. Psoriasis is an immune-mediated, genetic disease manifesting in the skin or joints or both. A diverse team of clinicians with a range of expertise is often needed to treat the disease. Psoriasis provides many challenges including high prevalence, chronicity, disfiguration, disability, and associated comorbidity. As over a third of the extended kindred included affected relatives besides siblings, in addition to an analysis of allele sharing between affected sibling pairs, a novel linkage strategy was applied that extracts full non-parametric information. There are several types of psoriasis, each of which varies in its signs and symptoms: Plaque psoriasis, Nail psoriasis, guttate psoriasis, Inverse psoriasis, Pustular psoriasis, Erythrodermic psoriasis. Psoriasis is thought to be an immune system to create problem that causes skin cells to grow faster than usual. In the most common type of psoriasis is known as plaque psoriasis, this is the rapid turnover of cells results in dry, scaly patches. The cause of psoriasis isn't fully understood. It's thought to be an immune system problem where infection-fighting cells attack to the healthy skin cells by mistake. Researchers believe that both genetics and environmental factors play a major role in the condition is not contagious. psoriasis triggers the Infections, such as strep throat or skin infections Weather, especially cold, dry conditions, Injury to the skin, such as a cut or scrape, a bug bite, or a severe sunburn, Smoking and exposure to secondhand smoke, Heavy alcohol consumption, Certain medications including lithium, high blood pressure drugs and anti-malarial drugs, Rapid withdrawal of oral or injected corticosteroids.