Abstract
As psoriasis is a common skin disorder, knowledge of the factors that may induce, trigger, or exacerbate the disease is of primary importance in clinical practice. Drug intake is a major concern in this respect, as new drugs are constantly being added to the list of factors that may influence the course of the disease. We report a patient with a psoriasiform drug eruption associated with the use of sodium valproate. Physicians should be aware of this type of reaction. Early detection of these cases has practical importance since the identification and elimination of the causative drug are essential for therapy success.
Highlights
Valproic acid (VPA), a branched chain aliphatic carboxylic acid, is a broad spectrum antiepileptic drug commonly used in childhood seizures, with good response rates and acceptable toxicity
Valproic acid is relatively free from skin allergy [3]
We report a patient with a psoriasiform drug eruption associated with the use of sodium valproate
Summary
Gulen Gul Mert, Faruk Incecik, Suhan Gunasti, Ozlem Herguner, and Sakir Altunbasak. As psoriasis is a common skin disorder, knowledge of the factors that may induce, trigger, or exacerbate the disease is of primary importance in clinical practice. Drug intake is a major concern in this respect, as new drugs are constantly being added to the list of factors that may influence the course of the disease. We report a patient with a psoriasiform drug eruption associated with the use of sodium valproate. Physicians should be aware of this type of reaction. Detection of these cases has practical importance since the identification and elimination of the causative drug are essential for therapy success
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