Abstract
A 35-year-old man was referred to the internal medicine department for acute hemiplegia with oral aphthous ulcers. The patient reported recurrent oral and genital ulcers more than 3 times a year. He also experienced one episode of peripheral thrombosis 1 year ago. The physical examination showed left hemiparesis with positive Babinski sign, hyperreflexia, and pseudofolliculitis in legs and trunk. The pathergy test was positive. Cerebral MRI showed a large mass hyperintense in T2 sequence in the regions of basal ganglia and corpus callosum with peripheral contrast enhancement and intensive edema around the lesion. The diagnosis of pseudotumoral neuro-Behçet disease was made on the basis of clinical history, the cerebral MRI result, and the exclusion of other tumoral and infectious diseases. The patient was treated with corticosteroids and cyclophosphamide with favorable outcome.
Highlights
A 35-year-old man was referred to the internal medicine department for acute hemiplegia with oral aphthous ulcers
Parenchymal involvement is characterized by focal lesions, mainly in the brainstem, basal ganglia, diencephalic structures, and internal capsules [3]
The prevalence of pseudotumoral neuro-Behçet disease (NBD) is estimated at 1.8% [2]
Summary
A 35-year-old man was referred to the internal medicine department for acute hemiplegia with oral aphthous ulcers. The patient reported recurrent oral and genital ulcers more than 3 times a year. He experienced one episode of peripheral thrombosis 1 year ago. The physical examination showed left hemiparesis with positive Babinski sign, hyperreflexia, and pseudofolliculitis in legs and trunk.
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