Abstract
Ependymoma is a brain tumor that develops from ependemic cells that lining the inside of all the ventricles of the brain. Ependymomas are twice as likely to appear in the region of the posterior cranial fossa. Pseudoprogression is a change that develops after surgical and/or chemoradiotherapy, caused by vascular changes leading to a transient increase in the permeability of the BBB. These changes coincide with early delayed reactions to radiotherapy and are considered as a subacute reaction of the brain. On MRI, there is a transient occurrence of foci that accumulate contrast for several weeks to 6 months or more after chemoradiotherapy. Dynamic control shows an improvement, which confirms the absence of true tumor growth. Changes take place without specific treatment. In the article, we give a rare clinical observation that shows the importance and effectiveness of dynamic MRI monitoring in differential diagnosis.
Highlights
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow, Russia Russian Peoples Friendship University of the Ministry of Education and Science of Russia, Moscow, Russia
Pseudoprogression is a change that develops after surgical and/or chemoradiotherapy, caused by vascular changes leading to a transient increase in the permeability of the BBB
On MRI, there is a transient occurrence of foci that accumulate contrast for several weeks to 6 months or more after chemoradiotherapy
Summary
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow, Russia Russian Peoples Friendship University of the Ministry of Education and Science of Russia, Moscow, Russia. Вскоре после завершения ЛТ у пациентов с опухолями головного мозга при МРТ с контрастным усилением (КУ) может наблюдаться усиление контрастности и увеличение размера зоны поражения с последующим улучшением или стабилизацией процесса даже без дальнейшего лечения. Псевдопрогрессирование же в 60% случаев развивается спустя 3 мес после завершения лечения и совпадает с ранними отсроченными реакциями на ЛТ и рассматривается как подострая реакция мозга. При МРТ отмечается преходящее увеличение размера и/или количества очагов, накапливающих контраст в течение 2–3 мес после химиолучевой терапии (60%), но описаны случаи возникновения в срок от нескольких недель до 6 мес.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
