Abstract
Cohnheim,1in 1865, described a case that presented anatomic characteristics similar to leukemia but without the changes in the blood found in that disease. For this disease he suggested the name pseudoleukemia. Since this original description, there have been recorded in the literature under this designation a variety of conditions, among which may be recognized Hodgkin's disease, lymphosarcoma, von Jaksch's disease, multiple myeloma, Gaucher's disease, Banti's disease, and even the lymph gland hyperplasias of tuberculosis and syphilis. This confusion has no doubt resulted from incomplete study of the material reported, and in consequence the interpretations contained in many of the reports deviate considerably from Cohnheim's original description. In 1912, Sternberg2critically reviewed the literature and emphasized the distinctive features of pseudoleukemia, definitely recording his belief that it is a distinct disease entity, as originally asserted by Cohnheim. The histologic changes of Hodgkin's disease separate it from pseudoleukemia, the
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