PS-C06-4: RELATIONSHIP BETWEEN URINARY MICROALBUMIN AND LIPID ACCUMULATION PRODUCT AND VISCERAL ADIPOSITY INDEX IN PATIENTS WITH ESSENTIAL HYPERTENSION

Abstract

Objective: To explore the relationship between urinary microalbumin and lipid accumulation product and visceral adiposity index in patients with essential hypertension. Design and method: A total of 463 essential hypertension patients admitted to the Department of Hypertension of the First Affiliated Hospital of Xinjiang Medical University from April 2020 to October 2021 were selected. Patients were grouped according to 24-hours urinary microalbumin and divided into normal 24-hours urinary microalbumin group and elevated 24-hours urinary microalbumin group to compare the clinical data of the two groups and analyze the risk factors of elevated urinary microalbumin. Results: The 24-hours urinary microalbumin was positively associated with lipid accumulation product and visceral adiposity index in patients with essential hypertension(all P < 0.01). The risk of elevated 24-hours urinary microalbumin may increase with increasing lipid accumulation product,visceral adiposity index. After adjusting for age,sex,admission systolic blood pressure,admission diastolic blood pressure,body mass index,triglycerides,high density lipoprotein cholesterol,serum creatinine,the OR (95%CI) of lipid accumulation product in the fourth quantile group was 4.770 (1.680∼13.545) compared with the first quantile of lipid accumulation product. The OR (95%CI) values of visceral adiposity index in the second,third and fourth quartile groups were 3.364 (1.330∼8.512),3.440 (1.249∼9.472),and 5.213 (1.556∼17.461),compared with the first quartile group of visceral adiposity index. Analysis of the receiver operating characteristic curve suggested that the risk of elevated urinary microalbumin increases when the lipid accumulation product is greater than 32.236 and the visceral adiposity index is greater than 2.031. Conclusion: When the lipid accumulation product and visceral adiposity index increase in patients with essential hypertension, they may lead to an increased risk of increased urinary microalbumin.